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Select Product Note CZRC
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At position 825 bp of the wild-type tp53 coding sequence, G, is mutated into TGATT. The mutated tp53 codes for a truncated protein containing 337 aa, 274 aa of which is identical to wildtype tp53. CZ266
Between 822 bp to 825 bp of the wild-type tp53 coding sequence, GCAG, is deleted. The mutated tp53 codes for a truncated protein containing 364 aa, 273 aa of which is identical to wildtype tp53. CZ267
4 bp deleted between 719 bp to 722 bp of the wild-type trpv1 coding sequence, AGAG, is deleted in exon 5. The mutated trpv1 codes for a truncated protein containing 250 aa, of which 813 aa are identical to wildtype trpv1. CZ268
In 704 bp of the wild-type trpv1 coding sequence, C, is mutated into GAG in exon 5. The mutated trpv1 codes for a truncated protein containing 252 aa, of which 813 aa are identical to wildtype trpv1. CZ269
Between 702 bp to 703 bp of the wild-type trpv1 coding sequence, GG, is mutated into AAA in exon 5. The mutated trpv1 codes for a truncated protein containing 256 aa, of which 813 aa are identical to wildtype trpv1. CZ270
This mutant has a T to G transversion at the kri1 exon 1-intron 1 consensus splicing donor site which causes a frameshift and a premature stop codon leading to the production of a truncated protein. CZ271
C to T nonsense mutation in topbp1 gene causing an earlier stop codon before the eighth BRCT (BRCA1 C-terminus) domain and a putative C-terminus nuclear localization signal (NLS) of TopBP1 protein CZ272
9-bp deletion plus 2-bp insertion predicted to encode a truncated Foxc1a protein with only the first 50 aa of Foxc1a plus 20 mutated aa. CZ274
As compared to the WT sequence, 107 bp is deleted (contain all exon 1) CZ275
Between 269 bp to 273 bp of the wild-type rbp1a coding sequence, GACGG, is deleted. CZ276
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