国家水生生物种质资源库国家斑马鱼资源中心 (China Zebrafish Resource Center)

基准单价：

营利性：¥2600(Adults)/Unit ¥1600(Embryos)/Unit ¥6000(Frozen sperm)/Unit
非营利性：¥1300(Adults)/Unit ¥800(Embryos)/Unit ¥3000(Frozen sperm)/Unit
价格详细
友情提示：为保证传代质量，野生型种鱼不支持少量订购，10对起订。
野生型环境毒理学用鱼，20尾起订。
特别提醒：“Availability”（品系提供方式）为“Frozen Sperm”的品系仅提供由冻存精子复苏的胚胎，不支持Adult/Embryos购买，下单时请务必选择Frozen Sperm，以免订单无效，耽误您的时间。
服　　务：由国家斑马鱼资源中心发货。
* 本收费用于补助CZRC所发生的运行和人工成本。
数量：

CZRC Catalog ID:	CZ401
Availability:	Frozen sperm
Genotype:	gbf1^tsu3994/+
Affected Gene:	gbf1
Genotyping:	pdf

GENOTYPE COMPOSITION

Genomic Feature	Zygosity	Parental Genotype	Lab of Origin	Construct
^tsu3994	heterozygous		Meng Lab

Background: AB Affectedgeneurl: unspecified Linetype: Mutant Previous Names: unspecified Background: AB Affectedgeneurl: unspecified Linetype: Mutant Previous Names: unspecified

Note:

tsu3994 mutant embryos carry a T to G single nucleotide substitution in the 23rd exon. This T to G mutation is predicted to cause a leucine to arginine substitution (L1246R for X5 isoform of Gbf1) in Gbf1 protein, which is highly conserved across animal species from Caenorhabditis elegans to human. According to the NCBI database, zebrafish gbf1 may produce five transcription variants (X1– X5), which all encode an identical protein except for a few amino acids in the non-conserved linker regions. The full-length Gbf1 X5 isoform (WT) consists of 1846 residues and the L1246R mutation resides in the highly conserved HDS2 domain.