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CZRC Catalog ID: MA2
Product: Desmin
Abbreviation: DESM
Isotype: IgG
Cellular Localization: Cytoplasm
Antibody type: Rabbit Polyclonal Antibody
Genecard: Desmin is one of the earliest protein markers for muscle tissue in embryogenesis as it is detected in the somites. Although it is present early in the development of muscle cells, it is only expressed at low levels, and increases as the cell nears terminal differentiation. Desmin is also important in muscle cell architecture and structure since it connects many components of the cytoplasm. Finally, desmin may be important in mitochondria function. Desmin-related myopathy (DRM or Desminopathy) is a subgroup of the myofibrillar myopathy diseases and is the result of a mutation in the gene that codes for desmin which prevents it from forming protein filaments, instead forming aggregates of desmin and other proteins throughout the cell. Recently, mutations were identified in patients suffered by an arrhythmogenic right ventricular cardiomyopathy (ARVC).
NoteInfo: 该抗体为CZRC与杭州华安生物技术有限公司(华安公司)合作开发,在CZRC下单订购即可享有团购价格在线订购时请在上传汇款凭证时上传此文件。CZRC会将有关订单转给华安公司,该抗体订单的付款、发货、售后及服务均由华安公司负责。
* 特别提醒:当您订购抗体时,勿需向CZRC进行支付;因CZRC网站有统一的订购流程,请您在“汇款凭证处”按要求上传此文件即可
Species Reactivity: Human, mouse, Zebrafish
Antibody Description: pdf
Recommended Dilutions:: WB: 1:1,000-1:2,000 ICC: 1:200 IHC: 1:200
Size: 100ul liquid
Phenotype:
Note:
Desmin
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