| CZRC Catalog ID: |
MA33 |
| Product: |
IRF7 |
| Abbreviation: |
IRF-7, IRF7 |
| Isotype: |
IgG |
| Cellular Localization: |
Nucleus, Cytoplasm |
| Antibody type: |
Recombinant Rabbit Monoclonal Antibody |
| Genecard: |
Interferon regulatory factor-1 (IRF-1) and IRF-2 have been identified as novel DNA-binding factors that function as regulators of both type I interferon (interferon-α and β) and interferon-inducible genes. The two factors are structurally related, particularly in their N-terminal regions, which confer DNA binding specificity. In addition, both bind to the same sequence within the promoters of interferon-α and interferon-β genes. IRF-1 functions as an activator of interferon transcription, while IRF-2 binds to the same cis elements and represses IRF-1 action. IRF-1 and IRF-2 have been reported to act in a mutually antagonistic manner in regulating cell growth; overexpression of the repressor IRF-2 leads to cell transformation while concomitant overexpression of IRF-1 causes reversion. IRF-1 and IRF-2 are members of a larger family of DNA binding proteins that includes IRF-3, IRF-4, IRF-5, IRF-6, IRF-7 and IFN consensus sequence-binding protein (ICSBP). |
| NoteInfo: |
该抗体为CZRC与杭州华安生物技术有限公司（华安公司）合作开发，在CZRC下单订购即可享有团购价格（在线订购时请在上传汇款凭证时上传此文件）。CZRC会将有关订单转给华安公司，该抗体订单的付款、发货、售后及服务均由华安公司负责。
* 特别提醒：当您订购抗体时，勿需向CZRC进行支付；因CZRC网站有统一的订购流程，请您在“汇款凭证处”按要求上传此文件即可。 |
| Species Reactivity: |
Human, Mouse, Rat, Zebrafish |
| Antibody Description: |
pdf |
| Recommended Dilutions:: |
WB: 1:1,000-1:2,000 ICC: 1:100-1:500 IHC: 1:50-1:200 FC: 1:50-1:100 |
| Size: |
100ul liquid |
