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CZRC Catalog ID: MA67
Product: LOX
Abbreviation: LOX
Isotype: IgG
Cellular Localization: Secreted, extracellular space.
Antibody type: Recombinant Rabbit Monoclonal Antibody
Genecard: The lysyl oxidase family of extracellular proteins includes LOX and four LOX-like enzymes, which are responsible for the deamination of peptidyl lysine residues of collagens and elastin. They also catalyze inter- and intra-crosslinking reactions. Overexpression of LOX may cause severe fibrotic degeneration due to its high resistance to degradative enzymes. Procollagen C-proteinase activity processes LOX from a precursor protein to a mature form. Activation of LOX occurs in normal developing and adult skin, and alterations in LOX expression and activity are associated with skin aging and senescence. LOX is crucial for development of the cardiovascular and respiratory systems. In addition, LOX plays a role in cancer, wound healing, as well as cell motility, chemotaxis and differentiation.
NoteInfo: 该抗体为CZRC与杭州华安生物技术有限公司(华安公司)合作开发,在CZRC下单订购即可享有团购价格在线订购时请在上传汇款凭证时上传此文件。CZRC会将有关订单转给华安公司,该抗体订单的付款、发货、售后及服务均由华安公司负责。
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Species Reactivity: Human, Mouse, Rat, Zebrafish
Antibody Description: pdf
Recommended Dilutions:: WB: 1:500-1:2,000 ICC: 1:100-1:500 IHC: 1:50-1:100 FC: 1:50-1:100
Size: 100ul liquid
Phenotype:
Note:
Protein-lysine 6-oxidase, Lysyl oxidase
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